Anti-CANX antibody produced in rabbit, affinity isolated antibody

Biochem/physiol Actions

Calnexin (CANX) takes care of protein folding. It binds to the target proteins which have only one glucose residue and aids in their folding. When the protein is released from CANX it is then trafficked to the Golgi apparatus for further modifications.

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General description

Calnexin (CANX) is a 67kDa transmembrane protein expressed in the endoplasmic reticulum. It is part of the lectin chaperone group. The gene ID of the protein is 821.

Immunogen

Dog Calnexin C-terminal sythetic peptide conjugated to KLH. Identical to human, mouse and rat calnexin sequences over these residues.

Physical form

PBS, pH 7..2, 50% glycerol, and 0.09% sodium azide

Specificity

Detects ~90 kDa.